4 Star Hotels in Syracuse
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
4 Star Hotels in Syracuse
Palazzo Artemide - VRetreats
Palazzo Artemide - VRetreats
9.4 out of 10, Exceptional, (619)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top neighborhoods in Syracuse
Ortigia
Syracuse's cultural Ortigia neighborhood offers lots of great attractions such as Cathedral of Syracuse and Piazza del Duomo.
Top landmarks in Syracuse
Lungomare di Ortigia
Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.
Keep exploring
Keep exploring
- Neighborhoods
- Landmarks
- Star Rating
- Accommodation Types
- Theme
- Top Cities in Italy
- More Hotels
- Most popular destinations
- More ways to book
- Hotels near Lungomare di Ortigia
- Hotels near Arenella Beach
- Hotels near Greek Theatre of Syracuse
- Hotels near Piazza del Duomo
- Hotels near Cathedral of Syracuse
- Hotels near Archaeological Park of Neapolis
- Hotels near Roman Amphitheatre of Syracuse
- Hotels near Porto Piccolo
- Hotels near Pista Ciclabile Siracusa
- Hotels near Ear of Dionysius
- Hotels near Castello Eurialo
- Hotels near Temple of Apollo
- Hotels near Castello Maniace
- Hotels near Ognina Beach
- Hotels near Fonte Aretusa
- Hotels near Tropical Aquarium of Syracuse
- Hotels near Spiaggia del Minareto
- Hotels near Catacombs of St. John
- Hotels near Museo Archeologico Regionale Paolo Orsi
- Hotels near Piazza Archimede
- Syracuse Beach Hotels
- Syracuse Family Hotels
- Syracuse Hotels with Parking
- Syracuse Pet Friendly Hotels
- Syracuse Hotels with Free Breakfast
- Syracuse Hotels with a Pool
- Syracuse Business Hotels
- Syracuse Resorts & Hotels with Spas
- Syracuse Luxury Hotels
- Syracuse Hotels with a Gym
- Syracuse Hotels with Kitchens
- Syracuse Cheap Hotels
- Hotels in Rome
- Hotels in Milan
- Hotels in Florence
- Hotels in Venice
- Hotels in Naples
- Hotels in Sorrento
- Hotels in Positano
- Hotels in Bologna
- Hotels in Palermo
- Hotels in Taormina
- Hotels in Amalfi
- Hotels in Verona
- Hotels in Turin
- Hotels in Bari
- Hotels in Como
- Hotels in Catania
- Hotels in Matera
- Hotels in Olbia
- Hotels in Lucca
- Hotels in Pisa
- Maniace Boutique Hotel Ortigia UNA Esperienze
- Nostos rooms & Apartments
- L'Approdo delle Sirene
- VOI Arenella Resort
- Archinuè Suite & Apartments
- Minareto
- Maison Ortigia
- B&B Casa D'Alleri
- Hotel Panorama
- Wellness & Spa Hotel Principe di Fitalia
- Residence Archimede
- Il Giardino di Sicilia
- Aretusa Vacanze B&B
- Calapetra Resort
- Fortaleza Charme House
- White Bay Resort
- Palazzo Alfeo
- Hotel Gargallo
- Hotel Livingston Siracusa
- Dimore delle Zagare Ortigia
- CinqueSuites Ortigia
- Residence Arco Antico
- Borgo Pantano
- Hotel Villamare
- Addauro Resort
- Rudy Arenaile
- B&B Spigolehouse
- B&B Marina di Ortigia
- Agriturismo Papyrus
- Italiana Resort Atrio
- Maecò Ortigia B&B
- Hotel Parco delle Fontane
Most popular destinations
Hotels
Hotels in San Vito Lo CapoHotels in OrtigiaHotels in VeronaHotels in BariHotels in MonopoliHotels in Trapani5 Star Hotels in TaorminaHotels in Castellammare del GolfoHotels in CefalùHotels in SalernoHotels in SorrentoCheap Hotels in FlorenceHotels in PortofinoBeach Hotels in PalermoHotels in BellagioHotels in PalermoHotels in CapriHotels in Cortina d'AmpezzoLuxury Hotels in CataniaHotels in BolognaLuxury Hotels in TropeaLuxury Hotels in San Vito Lo CapoHotels in La SpeziaHotels in TaorminaHotels in Monterosso al MareHotels in FlorenceBeach Hotels in TaorminaHotels in Amalfi4 Star Hotels in FlorenceHotels in Positano