Hotels in Syracuse

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Tonight
Feb 14 - Feb 15
Tomorrow
Feb 15 - Feb 16
This weekend
Feb 14 - Feb 16
Next weekend
Feb 21 - Feb 23

Where to stay in Syracuse?

B&B Spigolehouse
Deluxe Double Room

B&B Spigolehouse

8.4 out of 10, Very good, (24)
The price is CA $110
CA $136 total
includes taxes & fees
Feb 22 - Feb 23
B&B Spigolehouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Syracuse

Default Image

Ortigia

Syracuse's cultural Ortigia neighborhood offers lots of great attractions such as Cathedral of Syracuse and Piazza del Duomo.

See properties in Ortigia
Ortigia

Top landmarks in Syracuse

Lungomare di Ortigia

Lungomare di Ortigia

Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.

See properties in Lungomare di Ortigia
Lungomare di Ortigia

Learn more about Syracuse

Admired for its rich culture and seaside, Syracuse features attractions such as Temple of Apollo and Lungomare di Ortigia. This historical city has something for everyone including its archaeological sites, cafes, and sights like Piazza del Duomo and Cathedral of Syracuse.

See all hotels in Syracuse
Syracuse which includes street scenes as well as an individual female

Frequently asked questions

Can I book a refundable hotel in Syracuse?
If you’re looking for the flexibility to change your plans to Syracuse, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Syracuse?
Your animal companion is welcome at these pet-friendly hotels: Palazzo Artemide - VRetreats, Ortea Palace Hotel, Sicily, Autograph Collection, and 300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms. There are 105 alternatives on our site to choose from.
Which Syracuse hotels do our guests like for their central location?
Our guests love these properties for their good location: Algila’ Ortigia Charme Hotel and Palazzo Artemide - VRetreats.
Where can I stay in Syracuse if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 313 vacation homes. You can also book one of 926 apartments or 400 villas.
Where can I stay if I'm visiting Syracuse with my family?
Parents traveling with children may want to consider Algila’ Ortigia Charme Hotel, VOI Arenella Resort and 300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms. You can also check out 67 available options on our site.
Where should I stay in Syracuse for a vacation with my partner?
300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms, “B&B” Casa D’Alleri “Quadruple room in a historic home in” Ortigia “ and “B&B Casa D’Alleri” Double Rooms in a historic home in “Ortigia” are a few good options for a romantic getaway with your special someone. You can also see all 7 options on our site.
Where should I stay in Syracuse if I want a luxurious hotel?
Experience luxury when you stay at Grand Hotel Ortigia Siracusa, Wellness & Spa Hotel Principe di Fitalia and Minareto. Additionally, check out all 6 options on our site.
What will the weather in Syracuse be like during my trip?
August and July are typically the warmest months in Syracuse when the average temp is 78°F. February and January are the coldest months when the average temperature is 56°F. November and October are the months with the most rain.
Why should I book my Syracuse hotel with Hotels.com?
There are lots of reasons to book your Syracuse trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.