Hotels in Mytilene

Thu, Feb 19
Fri, Feb 20
February 2026
18
March 2026

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Feb 18 - Feb 19
Tomorrow
Feb 19 - Feb 20
This weekend
Feb 20 - Feb 22
Next weekend
Feb 27 - Mar 1

Where to stay in Mytilene?

Mythical Coast Wellness Retreat
Mythical Coast Wellness Retreat
Lesvos
  • Rejuvenating coastal escape with 3 indoor pools, spa treatments, and beachfront leisure.
Mythical Coast Wellness Retreat
The Loriet
The Loriet
Lesvos
  • Experience a serene beach stay with poolside lounging and premium comforts.
CA $86
CA $100 total
includes taxes & fees
Feb 26 - Feb 27
The Loriet
Heliotrope Hotels
Heliotrope Hotels
Lesvos
  • Step back into Old Town charm a short drive from Mytilene port and beaches.
CA $116
CA $132 total
includes taxes & fees
Feb 24 - Feb 25
Heliotrope Hotels
Elies Residences
Elies Residences
Lesvos
  • Secluded retreat on Lesvos with refreshing pool and pampering spa services.
Elies Residences
Theofilos Paradise Boutique Hotel
Theofilos Paradise Boutique Hotel
Lesvos
  • Unwind at this luxurious boutique haven steps from Port of Mytilene.
Theofilos Paradise Boutique Hotel
Oikies Small Elegant Houses
Oikies Small Elegant Houses
Lesvos
  • Exclusive poolside escape minutes from Mytilene Airport with free shuttle service.
CA $110
CA $122 total
includes taxes & fees
Feb 20 - Feb 21
Oikies Small Elegant Houses
Agora Apartments
Agora Apartments
Lesvos
  • Charming guesthouse near Port of Mytilene with easy access to local attractions.
CA $177
CA $195 total
includes taxes & fees
Feb 23 - Feb 24
Agora Apartments
Heliotrope The Studios
Heliotrope The Studios
Lesvos
  • Experience the tranquility of Lesvos with a serene terrace and lush garden setting.
CA $93
CA $103 total
includes taxes & fees
Feb 20 - Feb 21
Heliotrope The Studios
Olive Green Studios and Apartments
Olive Green Studios and Apartments
Lesvos
  • Coastal retreat with spa services just minutes from Ammoudéli beach.
CA $205
CA $228 total
includes taxes & fees
Feb 27 - Feb 28
Olive Green Studios and Apartments
Kaloni village apartments
Kaloni village apartments
Lesvos
  • Coastal village guesthouse steps from Skala Kallonis Beach with refreshing pool options.
Kaloni village apartments
Ouzo Stone House 1, with private pool
Ouzo Stone House 1, with private pool
Lesvos
CA $314
CA $350 total
includes taxes & fees
Feb 27 - Feb 28
Ouzo Stone House 1, with private pool
Ouzo Stone House 2, with private pool
Ouzo Stone House 2, with private pool
Lesvos
CA $314
CA $350 total
includes taxes & fees
Feb 27 - Feb 28
Ouzo Stone House 2, with private pool
View all properties

Check out pet-friendly hotels in Mytilene

Agora Apartments

Agora Apartments
Lesvos
CA $177
CA $195 total
includes taxes & fees
Feb 23 - Feb 24
Agora Apartments

Heliotrope The Studios

Heliotrope The Studios
Lesvos
CA $93
CA $103 total
includes taxes & fees
Feb 20 - Feb 21
Heliotrope The Studios

Heliotrope Hotels

Heliotrope Hotels
Lesvos
CA $116
CA $132 total
includes taxes & fees
Feb 24 - Feb 25
Heliotrope Hotels

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
Theofilos Paradise Boutique Hotel

The Loriet

The Loriet
Lesvos
CA $86
CA $100 total
includes taxes & fees
Feb 26 - Feb 27
The Loriet
View all properties

You can also stay at hotels with a pool in Mytilene

Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
Mythical Coast Wellness Retreat

Elies Residences

Elies Residences
Lesvos
Elies Residences

The Loriet

The Loriet
Lesvos
CA $86
CA $100 total
includes taxes & fees
Feb 26 - Feb 27
The Loriet

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
Theofilos Paradise Boutique Hotel

Heliotrope Hotels

Heliotrope Hotels
Lesvos
CA $116
CA $132 total
includes taxes & fees
Feb 24 - Feb 25
Heliotrope Hotels

Oikies Small Elegant Houses

Oikies Small Elegant Houses
Lesvos
CA $110
CA $122 total
includes taxes & fees
Feb 20 - Feb 21
Oikies Small Elegant Houses
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top landmarks in Mytilene

Bus Station

4.0/5 (1 review)
Bus Station is worth a visit, located 0.4 mi (0.6 km) from central Mytilene.
See properties

Mytilini Castle

4.6/5 (11 reviews)
You might want to get your camera out and head to Mytilini Castle— just one of the landmarks located 1 mi (1.7 km) from central Mytilene.
See properties

Thermi Beach

Whether you want to collect beach glass or watch the sunset, Thermi Beach is a spot you might want to check out when visiting central Pirgi Thermis. Catch the sunset by the shore at Plaz Kanóni, just a short walk away.
See properties

Thermes Gera Hot Springs

Thermes Gera Hot Springs is 4.1 mi (6.5 km) from central Mytilene, why not stop by during your stay.
See properties

Roman Aqueduct at Moria

If you're planning a bit of sightseeing during your trip, head to Roman Aqueduct at Moria— just one of the landmarks located 3 mi (4.9 km) from central Mytilene.
See properties

Church of Taxiarches

Church of Taxiarches is 2.2 mi (3.5 km) from central Mytilene, why not stop by during your stay.
See properties

Teriade Museum

If visiting museums in Varia are on your list, you might want to check out the upcoming exhibitions at Teriade Museum, located in the heart of town. If you want to see more of the museums in Varia, you can easily walk to Theophilos Museum.
See properties

Olive-press Museum of Archipelagos Society

The center of Mytilene is home to cultural attractions like Olive-press Museum of Archipelagos Society, so you might want to stop by during your stay. If you want to experience more of the culture Mytilene has to offer, head to Mytilini Castle, Port of Mytilene, and Bus Station.
See properties

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

See all hotels in Mytilene
Mitylene Island, or better known as Lesvos, Greece. There seriously are 50 different shades of blue in this country. Enjoy practically empty beaches and amazing food on this sleepy little island just off the west coast of Turkey.

http://www.hecktictravels.com/shades-of-blue

#Greece #Lesvos #Travel
Photo by Hecktic Travels

Check out reviews of Mytilene hotels guests love

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

10/10 Excellent
"The room was impeccable. The staff were courteous enough to let us check in a few hours early after a long trip. "
Micaela 1-night trip
Posted 3 weeks ago
Theofilos Paradise Boutique Hotel
Hotel Lesvion

Hotel Lesvion

10/10 Excellent
"First of all, all the hotel staff were extremely friendly, kind, and helpful. We thank them all individually. The hotel's location, cleanliness, and the variety and quality of the breakfasts were excellent. We are eagerly looking forward to staying at this hotel again. Thank you very much."
Ebru 3-night trip
Posted 2 months ago
Hotel Lesvion
The Loriet

The Loriet

10/10 Excellent
"Temizlik, kaliteli hizmet, çözüm odakkı müşteri iletişimi, vb."
Engin 3-night trip
Posted 3 months ago
The Loriet
Agora Apartments

Agora Apartments

10/10 Excellent
"Great facility, but do not use your car to reach the property. No close by parking, narrow streets. Great communication friendly staff. "
Ali 1-night trip
Posted 4 months ago
Agora Apartments
Paradisos studios

Paradisos studios

10/10 Excellent
"This hotel is owner operated. Owner directly helped me to check in. Room was clean and spacious. Phenomenal value for the money. It is the 3rd time we have stayed at Paradisos. "
Chris 3-night trip
Posted 4 months ago
Paradisos studios
Heliotrope Hotels

Heliotrope Hotels

10/10 Excellent
"Stayed here both last year and this summer. Very convenient location between airport and city centre. There is a bus stop right across the hotel but taxi is also very affordable. They have a nice buffet breakfast and rooms are very clean. Friendly staff as well. "
Banu 2-night trip
Posted 6 months ago
Heliotrope Hotels
Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat

2/10 Terrible
"I booked a junior suite. The description does not match the room. The room was to have a balcony and it does not. It was a basic room of 30 square metres with two single beds pushed together and a chair and small table. The service was terrible. The person at teh front desk in the morning was rude and basically could not wait to get me out. This was out of character witht he wonderful hospitality elsewhere on the island. I would NEVER recommend this place. "
Alissa 1-night trip
Posted 7 months ago
Mythical Coast Wellness Retreat
Lasia Hotel

Lasia Hotel

10/10 Excellent
"Very friendly stuff. Helpful and nice Close to public transport and a cross from a very nice beach"
Sharon 2-night trip
Posted 8 months ago
Lasia Hotel
Oikies Small Elegant Houses

Oikies Small Elegant Houses

10/10 Excellent
"Great place! Don’t look for anywhere else!"
ATAMAN 2-night trip
Posted 8 months ago
Oikies Small Elegant Houses

Frequently asked questions

How much does a hotel room cost in Mytilene?
You can discover great hotels in Mytilene from CA $100 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mytilene that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Mytilene hotels?
Discover great deals on Mytilene hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Mytilene hotels.
Can I book Mytilene hotels with free cancellation?
To book a refundable Mytilene hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are the top-rated luxury hotels in Mytilene?
Some of the most popular luxury hotels in Mytilene are Theofilos Paradise Boutique Hotel, Elysion Hotel, and Mythical Coast Wellness Retreat. Theofilos Paradise Boutique Hotel is a luxury hotel with a high guest rating amongst our travelers, and it offers 4 hot springs, a full-service spa and a seasonal outdoor pool. Elysion Hotel and Mythical Coast Wellness Retreat are also popular luxury stays in great Mytilene locations.
What are some of the best Mytilene beach hotels?
For a beachy vacation in Mytilene, Thermi Beach and Ágios Ermogénis are some of the best places to visit. Stay at a well-reviewed Mytilene beach hotel and enjoy your vacation. Check out Mythical Coast Wellness Retreat if you're after a hotel that's near the water. With a beachfront setting plus an outdoor pool and a full-service spa, our travelers rate it highly at 8.6 out of 10.
What are some of the best hotels in Mytilene for couples?
Choose a top-rated Mytilene romantic hotel and enjoy your couple's getaway. Our travelers love Elysion Hotel, a hotel with 2 restaurants and an outdoor pool. Another romantic hotel with top reviews is Mythical Coast Wellness Retreat. This hotel offers a beach and 5 restaurants for a perfect stay. Discover more hotels in Mytilene on Hotels.com for couples by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are the top Mytilene hotels with a pool?
For a little extra luxury, discover some of the best Mytilene hotels with a pool. Theofilos Paradise Boutique Hotel is a great hotel with a seasonal outdoor pool and a children's pool, and a guest rating of 9.6 out of 10. Plus, you can make the most of its 4 hot springs and full-service spa. Lasia Hotel is a popular hotel that features an outdoor pool along with a bar/lounge and a free buffet breakfast. To find more stays in Mytilene with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Mytilene hotels with free parking?
If you're driving, a great Mytilene hotel with free parking is a bonus. Our travelers' favorites include:
What are the top Mytilene boutique hotels?
Book your stay at a stylish boutique hotel in Mytilene. Theofilos Paradise Boutique Hotel is a popular hotel with our travelers, offering guests a seasonal outdoor pool and a children's pool as well as individually furnished guestrooms with down comforters and minibars.
What are some popular hotels in central Mytilene?
For hotels in central Mytilene, check out Theofilos Paradise Boutique Hotel and Hotel Lesvion. Travelers love Theofilos Paradise Boutique Hotel for its location, as well as the seasonal outdoor pool, children's pool and 4 hot springs this hotel offers. Hotel Lesvion is another popular central hotel with a restaurant, a bar/lounge and a free buffet breakfast.
Can I book a refundable hotel in Mytilene?
If you need the flexibility to change your travel plans to Mytilene, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mytilene if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 15 vacation homes. You can also book one of 22 apartments or 20 villas.

Find out more about Mytilene

Explore Mytilene: A Tapestry of Ancient Ruins and Island Serenity

Nestled on the lush island of Lesvos, Mytilene is a captivating blend of history, culture, and stunning landscapes. Explore the charming Mytilini town, where vibrant streets are lined with neoclassical architecture and inviting cafés. The impressive Mytilene Castle offers panoramic views and a glimpse into the island's storied past. Discover archaeological treasures and museums that celebrate Lesvos' rich heritage. With its picturesque harbour and serene beaches, Mytilene is perfect for romantic getaways or cultural explorations. Whether wandering through ancient ruins or indulging in local delicacies, Mytilene promises an unforgettable Greek escape off the beaten path. For unmissable hotel rates in Mytilene, be sure to check out Hotels.com's Last-Minute DealsOpens in a new window on travel.

Discover great hotels in Mytilene

Mytilene offers a diverse range of accommodations, from budget-friendly hotels to more upscale options. Visitors can find charming guesthouses and modern hotels, all within easy reach of the city’s attractions. Whether you're seeking a cozy stay or a more luxurious experience, Mytilene has plenty to choose from. Here are some of the most popular hotels with our travelers in Mytilene:

  1. Ariadnes Holiday AccommodationOpens in a new window: This charming 3.0-star guesthouse is perfect for leisure travelers seeking a beach vacation experience. With direct access to the beach, guests can easily soak up the sun and enjoy the picturesque seaside views. The inviting atmosphere and comfortable accommodations create a relaxing retreat, making it a popular choice among frequent travelers who appreciate a laid-back yet enjoyable getaway.
  2. Ariadnes Holiday Accommodation IIOpens in a new window: Another delightful 3.0-star guesthouse, Ariadnes Holiday Accommodation II offers a similarly appealing beach vacation experience. Featuring direct access to the beach, this property allows guests to immerse themselves in the coastal beauty and tranquility. The combination of cozy lodging and the serene environment ensures that travelers looking for a rejuvenating escape will find their time here truly satisfying.
  3. Aeolis Apartments & StudiosOpens in a new window: For those in search of a unique, spa-themed getaway, Aeolis Apartments & Studios is an excellent choice. This 3.0-star guesthouse features a natural hot spring nearby, allowing guests to indulge in soothing hot spring experiences. The full-service spa offers various treatments, including Swedish massages and couples treatment rooms, creating the perfect atmosphere for relaxation. Travelers looking for a distinctive experience will appreciate the pet-friendly amenities and tranquil setting, making it a preferred destination for spa enthusiasts.

Top locations to stay in Mytilene

In Mytilene, Lesvos, North Aegean Islands, Greece, notable places to stay include Lesvos, Apidias Lakkos, and Ano Chalikas. Lesvos boasts rich museums and ruins, Apidias Lakkos offers stunning island views, and Ano Chalikas features charming local culture. For first-time visitors, Lesvos is the best choice, providing easy access to Mytilini's vibrant town centre and attractions.

  1. LesvosOpens in a new window: Lesvos is a fantastic destination for travelers looking to immerse themselves in rich history and culture. With numerous museums showcasing the island's artistic heritage and archaeological ruins that tell the stories of ancient civilizations, you’ll find plenty to explore. The island is also known for its stunning natural landscapes, charming villages, and warm hospitality. Enjoy a leisurely stroll through local markets where you can shop for unique handicrafts and local delicacies. Don't miss the chance to visit the picturesque coastal towns, where vibrant cultural attractions and outdoor activities await.
  2. Apidias LakkosOpens in a new window: Apidias Lakkos offers a serene escape on the beautiful island of Lesvos, perfect for those seeking a quieter experience. This area is known for its breathtaking natural surroundings, making it ideal for nature lovers and those wanting to relax by the sea. You can explore the nearby beaches, which boast crystal-clear waters and stunning views. The region’s rich local culture and small community vibe provide opportunities to enjoy authentic experiences, including local crafts and traditional cuisine.
  3. Ano ChalikasOpens in a new window: Ano Chalikas is a charming spot on Lesvos that captures the essence of traditional island life. It's a great place to stay if you’re looking to experience the local culture and hospitality. The area is surrounded by beautiful landscapes and has a range of hiking trails that allow you to connect with nature. Here, you can also enjoy local shops offering handmade goods and discover the history reflected in the architecture of the village. The laid-back atmosphere is perfect for unwinding while soaking in the stunning views of the Aegean Sea.

Things to do in Mytilene

Mytilene enchants visitors with its stunning coastal views, lush hills, and charming harbours. Explore the rich history through ancient ruins and impressive architecture, or relax on serene beaches. Whether hiking through scenic landscapes or enjoying local cuisine by the water, this captivating destination promises unforgettable experiences.

  • Molyvos CastleOpens in a new window – Step into history at Molyvos Castle, perched high above the town. As you explore its ancient walls, you’ll be rewarded with breathtaking views of the surrounding landscape and the Aegean Sea. The castle’s impressive architecture and rich history make it a perfect spot for photography and a leisurely stroll.
  • MólyvosOpens in a new window – Spend a relaxing day at Mólyvos beach, where golden sands meet crystal-clear waters. It’s an ideal location for sunbathing, swimming, or simply enjoying a leisurely walk along the shoreline. The picturesque village nearby offers charming cafes and shops to explore after a day in the sun.
  • Eftalou Hot SpringsOpens in a new window – Treat yourself to a rejuvenating experience at Eftalou Hot Springs, known for its therapeutic waters. A soak here is not just refreshing; it’s a chance to unwind and take in the natural beauty surrounding you. Don’t forget your swimsuit!
  • Monastery of Saint RaphaelOpens in a new window – Visit the serene Monastery of Saint Raphael, an important religious site on the island. The stunning architecture and peaceful atmosphere make it a perfect spot for contemplation. Take a moment to appreciate the intricate details and the beautiful gardens that surround this sacred place.
  • Mytilini CastleOpens in a new window – Discover the grandeur of Mytilini Castle, a historic fort that offers a glimpse into the island's past. Wander through its expansive grounds and admire the impressive stonework. The castle's vantage point provides another stunning view of the city and beyond, making it a must-see for history enthusiasts.

4 tips for savvy savings when booking a hotel in Mytilene

  1. Book for the cheapest times: The most affordable time to visit Mytilene is during February, November, and December, when hotel prices are lower. To fully appreciate the city's historical and cultural offerings, a stay of at least 4 to 5 days is recommended. This budget-friendly timeframe allows visitors to explore essential landmarks and attractions, including museums, churches, the castle, ancient ruins, and the picturesque marina. With the chance that prices may drop during these months, it presents a great value for money for those travelling on a budget.
  2. Look for last-minute deals on Hotels.com: To discover last-minute deals to Mytilene, begin by checking the DealsOpens in a new window or Last-Minute DealsOpens in a new window section on Hotels.com, where you may find discounted hotel rates as your travel date approaches. Consider enabling email alerts or push notifications to stay informed about flash sales and exclusive promotions, so you don’t miss opportunities to save. Additionally, Smart ShoppingOpens in a new window is a helpful comparison tool within the app that allows you to compare hotel prices and amenities, ensuring you’re more likely to see the best options available. This way, you can book your last-minute getaway with confidence.
  3. Be flexible with dates: Prices can fluctuate based on various factors, including the hotel's location, star rating, and time of year. Therefore, being flexible with your travel dates may help you save on your stay at a hotel in Mytilene. For those seeking distinctive accommodations, boutique hotels often provide a more personalized experience and occasionally better value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price is on the higher end, we’ll suggest more affordable dates, increasing the likelihood that you’ll find a better deal.
  4. Consider your location: Staying near major attractions or city centres can provide convenience, but it often comes with a higher price tag. For those seeking more affordable options, consider hotels in less central areas or neighbourhoods, which usually tend to be cheaper while still offering reasonable access to the sites you plan to explore. You might also look into independent hotels located a bit further out, as they can offer a more authentic and budget-friendly experience.

Best time to go to Mytilene

Mytilene experiences its lowest average temperature in January, at 49.3°F (9.6°C), while August is the hottest month, with an average temperature of 80.1°F (26.7°C). January is typically the wettest month. If you’re looking to soak up the lively atmosphere in Mytilene, June to August are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is sunny, with no rainfall. However, if you prefer a more relaxed experience, January, February, and December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

Keep exploring