Hotels in Irene

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Check prices for these dates

Tonight
Apr 26 - Apr 27
Tomorrow
Apr 27 - Apr 28
Next weekend
May 2 - May 4
In two weeks
May 9 - May 11

Where to stay in Irene?

Holiday Inn Express & Suites Yankton by IHG
Exterior

Holiday Inn Express & Suites Yankton by IHG

2.5 star property
9.2 out of 10, Wonderful, (388)
The price is CA $158
CA $181 total
includes taxes & fees
May 11 - May 12
Holiday Inn Express & Suites Yankton by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Irene

You can explore the area's natural beauty at Lincoln Park during your stay.

See all hotels in Irene
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to get 25% or more off selected hotels, plus 1 reward night for every 10 nights you stay. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers recommend in Irene?
Guests like Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!.
Can I book refundable hotels in Irene?
If you’re looking for the flexibility to change your plans to Irene, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Irene be like during my vacation?
July and August are typically the warmest months in Irene when the average temp is 72°F. January and February are the coldest months when the average temperature is 26°F. June and May are the months with the most rain.
Why should I book my Irene accommodation with Hotels.com?
There are lots of reasons to book your Irene trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Irene

Find out more about Irene

If you're looking for a place to get away, look no further than Irene. Whether you're planning to stay for a night or for the week, the area around Irene has accommodations to fit every need. Search for hotels in Irene with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Irene hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Irene hotel deals are here with our lowest price guarantee.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com™ app users and Hotels.com™ Rewards members. Limited availability, blackout periods may apply.

Hotels.com Rewards members save more, as compared to non-members shopping on Hotels.com. Members 18+. Eligible properties only. Reward Night worth average daily rate of 10 stamps (excluding taxes/fees). Taxes/fees payable on reward night. Booking exclusions apply, see terms https://ca.hotels.com/lp/b/terms-of-service?pos=HCOM_CA&locale=en_CA.