Hotels in San Cosme y Damian

your current months are January, 2025 and February, 2025.
January 2025
February 2025
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Where to stay in San Cosme y Damian?

Top landmarks in San Cosme y Damian

Guarani Jesuit Ruins of San Cosme and San Damián

Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.

See properties in Guarani Jesuit Ruins of San Cosme and San Damián
Guarani Jesuit Ruins of San Cosme and San Damián

Buenaventura Suarez Planetarium

You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area.

See properties in Buenaventura Suarez Planetarium
Buenaventura Suarez Planetarium

Learn more about San Cosme y Damian

San Cosme y Damian is well-known for its attractions such as Guarani Jesuit Ruins of San Cosme and San Damián and Buenaventura Suarez Planetarium.

See all hotels in San Cosme y Damian

Frequently asked questions

Can I book a refundable hotel in San Cosme y Damian?
If you’re looking for the flexibility to change your plans to San Cosme y Damian, most hotels offer refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in San Cosme y Damian be like during my trip?
January and February are typically the warmest months in San Cosme y Damian when the average temp is 80°F. July and June are the coldest months when the average temperature is 62°F. October and November are the months with the most rain.
Why should I book my San Cosme y Damian hotel with Hotels.com?
There are plenty of reasons to book your San Cosme y Damian travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.