Hotels in Santa Cruz

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Where to stay in Santa Cruz?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Cruz

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.

San Lorenzo Cathedral which includes a garden

Frequently asked questions

Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Santa Cruz?
Your furry friend can stay with you at these pet-friendly hotels: Hotel LP Equipetrol, Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. There are 10 options to choose from on our site.
Which Santa Cruz hotels do our guests like for their great location?
Our guests rave about the location of these properties: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Camino Real Hotel and Radisson Hotel Santa Cruz.
Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?
An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 14 choices on our site.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 19 vacation homes. In addition, you can choose from 98 apartments.
Where can I stay if I'm traveling to Santa Cruz with my kids?
Parents traveling with children may want to consider Marriott Santa Cruz de la Sierra Hotel, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. You can also see 12 options on our site.
Where should I stay in Santa Cruz for a getaway with my partner?
Buganvillas Hotel Suites & Spa is a good option for a romantic getaway with your special someone.
Where should I stay in Santa Cruz if I'm looking for a luxury hotel?
Experience luxury when you stay at Marriott Santa Cruz de la Sierra Hotel, Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Additionally, browse all 6 options on our site.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.