Hotels in Santa Cruz

your current months are December, 2024 and January, 2025.
December 2024
January 2025

Find and book your perfect stay

Earn rewards on every night you stay
Save more with Member Prices
Free cancellation options if plans change

Where to stay in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel
Property amenity
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
9.0 out of 10, Wonderful, (165)
The price is CA $135
CA $135 total
includes taxes & fees
Nov 29 - Nov 30
Marriott Santa Cruz de la Sierra Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Cruz

Plaza 24 de Septiembre showing heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.

See properties
Plaza 24 de Septiembre

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Alfonsina Hotel Boutique by Inboccaluppo, TRYP by Wyndham Santa Cruz and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are all accommodations that are popular with guests.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Swissôtel Santa Cruz De La Sierra. There are 11 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Santa Cruz?
Your furry friend can stay with you at these pet-friendly hotels: Hotel LP Equipetrol, Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. There are 10 options to choose from on our site.
Which Santa Cruz hotels do our guests like for their great location?
Our guests rave about the location of these properties: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Camino Real Hotel and Radisson Hotel Santa Cruz.
Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?
An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 14 choices on our site.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 17 vacation homes. In addition, you can choose from 72 apartments.
Where can I stay if I'm traveling to Santa Cruz with my kids?
Parents traveling with children may want to consider Marriott Santa Cruz de la Sierra Hotel, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. You can also see 12 options on our site.
Where should I stay in Santa Cruz for a getaway with my partner?
Buganvillas Hotel Suites & Spa is a good option for a romantic getaway with your special someone.
Where should I stay in Santa Cruz if I'm looking for a luxury hotel?
Experience luxury when you stay at Marriott Santa Cruz de la Sierra Hotel, Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Additionally, browse all 6 options on our site.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.