Photo by Eddie Melendez

Hotels in Santa Isabel

your current months are December, 2024 and January, 2025.
December 2024
January 2025

Find and book your perfect stay

Earn rewards on every night you stay
Save more with Member Prices
Free cancellation options if plans change

Where to stay in Santa Isabel?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Isabel

The region around Santa Isabel is home to attractions such as Coamo Springs and Marina de Salinas.

Photo by Eddie Melendez
Open Photo by Eddie Melendez

Frequently asked questions

Can I book refundable accommodations in Santa Isabel?
If you want the flexibility to change your travel plans to Santa Isabel, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay with my pet in Santa Isabel?
Your animal companion is welcome at these pet-friendly hotels: Hotel Las Vegas and Hotel Las Vegas, Queen Suite.
Where can I stay in Santa Isabel if I want a vacation rental instead of a traditional hotel?
You’ll find 5 vacation homes on our site.
Where can I stay if I'm traveling to Santa Isabel with my family?
Parents traveling with children may want to consider Hotel Las Vegas.
Where should I stay in Santa Isabel for a trip with my partner?
Hotel Las Vegas is a great option for a romantic getaway.
What will the weather in Santa Isabel be like during my vacation?
With an average temperature of 76°F during the coldest months, Santa Isabel is a great place to visit any time of year.
Why should I book my Santa Isabel hotel through Hotels.com?
There are plenty of reasons to book your Santa Isabel travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.