Experience luxury and convenience near iconic attractions like Busch Stadium. Take a break from exploring to indulge your senses with great food and drink.
St. Louis Lambert Intl. Airport (STL) - 26 min drive
St. Louis, MO (SUS-Spirit of St. Louis) - 32 min drive
St. Louis Gateway Station - 14 min walk
Kirkwood Station - 24 min drive
8th and Pine Station - 13 min walk
Convention Center Station - 16 min walk
Stadium Station - 19 min walk
Restaurants
Rosalita's Cantina - 6 min walk
Grand Hall Lounge Union Station - 11 min walk
Hair of the Dog - 7 min walk
Peabody Lounge - 6 min walk
Medina Mediterranean Grill - 5 min walk
About this property
21C Museum Hotel St Louis
21C Museum Hotel St Louis puts you in a great location, within just a 10-minute walk of City Museum and Enterprise Center. Guests indulge in massages, then grab a bite to eat at the coffee shop/cafe. Other features of this luxurious hotel include an indoor pool, a bar/lounge, and a fitness center. Fellow travelers say great things about the pool and helpful staff. Public transportation is close by: 8th and Pine Station is just 13 minutes by foot.
Languages
English
At a glance
Hotel size
104 rooms
Arriving/Leaving
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21
Check-out time is 11:00 AM
Special check-in instructions
Front desk staff will greet guests on arrival
Required at check-in
Credit card, debit card, or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
Children
No cribs (infant beds)
Pets
Pets allowed (dogs only)*
Service animals welcome
Internet
Free WiFi in public areas
Free WiFi in rooms
Parking
Onsite valet parking (USD 45 per day; includes in/out privileges)
Other information
Smoke-free property
Property amenities
Food and drink
Cooked-to-order breakfast (surcharge) each morning 6:30 AM–1:00 PM
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
Fees & policies
Mandatory fees
You'll be asked to pay the following charges by the property at check-in or check-out. Fees may include applicable taxes:
Service fee: USD 5 per accommodation, per stay
Optional extras
Cooked-to-order breakfast is offered for an extra charge of approximately USD 10 to 25 per person
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Parking
Valet parking costs USD 45 per day with in/out privileges
Pool, spa, & gym (if applicable)
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation
Policies
Guests can rest easy knowing there's outdoor lighting on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards. Cash is not accepted.
Property Registration Number 832174967
Also known as
21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)
Frequently asked questions
Does 21C Museum Hotel St Louis offer free cancellation for a full refund?
Yes, 21C Museum Hotel St Louis does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.
Is there a pool at 21C Museum Hotel St Louis ?
Yes, there's an indoor pool.
Are pets allowed at 21C Museum Hotel St Louis ?
Yes, dogs are welcome. There's a charge of USD 100 per accommodation, per stay. Service animals are exempt from fees.
Is parking offered on site at 21C Museum Hotel St Louis ?
Yes. Valet parking costs USD 45 per day.
What are the check-in and check-out times at 21C Museum Hotel St Louis ?
Check-in start time: 4:00 PM; Check-in end time: 11:00 AM. Check-out time is 11:00 AM.
Is there an onsite casino at 21C Museum Hotel St Louis ?
No, this hotel doesn't have a casino, but Horseshoe St. Louis Casino (3-min drive) and Casino Queen (4-min drive) are both nearby.
What is there to do at 21C Museum Hotel St Louis and nearby?
21C Museum Hotel St Louis has an indoor pool and a steam room, as well as spa services.
Are there restaurants at or near 21C Museum Hotel St Louis ?
Yes, there's an onsite restaurant.
What's the area around 21C Museum Hotel St Louis like?
21C Museum Hotel St Louis is in Downtown West, a short 12-minute walk from St. Louis Union Station and 6 minutes' walk from City Museum. Travelers love the hotel's prime location.
21C Museum Hotel St Louis Reviews
Reviews
9.2
Wonderful
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.4/10
Cleanliness
9.2/10
Staff & service
9.2/10
Amenities
9.4/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
10/10 Exceptional
14 Jan 2025
KELLIE
KELLIE, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
14 Jan 2025
Staci
Staci, 2-night trip
Verified Hotels.com guest review
8/10 Very good
13 Jan 2025
Verified traveller
1-night trip
Verified Hotels.com guest review
10/10 Exceptional
12 Jan 2025
Perfection!
10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!
Becky
Becky, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
12 Jan 2025
Great stay in unique hotel
I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.
Patrice
Patrice, 2-night business trip
Verified Hotels.com guest review
10/10 Exceptional
9 Jan 2025
Irna
Irna, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
8 Jan 2025
Stephan
Stephan, 1-night business trip
Verified Hotels.com guest review
10/10 Exceptional
7 Jan 2025
Alexander
Alexander, 2-night trip
Verified Hotels.com guest review
10/10 Exceptional
7 Jan 2025
Dimonica
Dimonica, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
4 Jan 2025
Highly recommend!
Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!
regine
regine, 1-night trip with friends
Verified Hotels.com guest review
10/10 Exceptional
2 Jan 2025
Verified traveller
1-night business trip
Verified Hotels.com guest review
10/10 Exceptional
2 Jan 2025
Monique
Monique, 2-night trip
Verified Hotels.com guest review
10/10 Exceptional
2 Jan 2025
Bell
Bell, 2-night family trip
Verified Hotels.com guest review
10/10 Exceptional
2 Jan 2025
Christopher
Christopher, 1-night family trip
Verified Hotels.com guest review
10/10 Exceptional
1 Jan 2025
Great stay
Fabulous hotel, decor amazing, loved the museum, room was perfect
Denise
Denise, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
31 Dec 2024
David
David, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
30 Dec 2024
Confirm online reservation
I had reserved two rooms. Both double queen beds. Called because I wanted to reassure these were near each other. Told no but I could change out one double queen doom for a king and they would be directly across from each other. Well that ended up not being the case. Down the hall and around a corner. Disappointed because I would have kept the original reservations because the king room is quite small in comparison but was willing to switch with rooms directly across. And then they were not.
The hotel was beautiful. Very clean.
Pam
Pam, 2-night family trip
Verified Hotels.com guest review
10/10 Exceptional
30 Dec 2024
Try 21C
It was a wonderful surprise-exceeded expectations.
Verified traveller
1-night family trip
Verified Hotels.com guest review
10/10 Exceptional
30 Dec 2024
Michael
Michael, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
30 Dec 2024
Molly
Molly, 1-night trip
Verified Hotels.com guest review
10/10 Exceptional
30 Dec 2024
Eric
Eric, 1-night trip
Verified Hotels.com guest review
8/10 Very good
30 Dec 2024
Could use some tweaks to service...
Check in was amazing. After learning our sons were active military getting some leave time to see their parents, they provided the boys $40 dinner credits and 4 drinks for our family. However, upon check out the desk clerk wouldn't honor the credit. Odd and unfortunate. The art exhibit was the best we've seen in our stays of this chain.