Photo by Tony Oteromarrero

Hotels in Desert Center

Free cancellation options if plans change
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Check prices for these dates

Tonight
May 21 - May 22
Tomorrow
May 22 - May 23
This weekend
May 23 - May 25
Next weekend
May 30 - Jun 1

Where to stay in Desert Center?

Learn more about Desert Center

You can explore the area's natural beauty at Joshua Tree National Park during your stay.

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Photo by Tony Oteromarrero
Open Photo by Tony Oteromarrero
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to get 25% or more off selected hotels, plus 1 reward night for every 10 nights you stay. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

Can I book a refundable hotel in Desert Center?
If you’re looking for the flexibility to change your plans to Desert Center, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Desert Center be like during my vacation?
July and August are typically the warmest months in Desert Center when the average temp is 93°F. December and January are the coldest months when the average temperature is 59°F. December and August are the months with the most rain.
Why should I book my Desert Center hotel through Hotels.com?
There are lots of reasons to book your Desert Center trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Desert Center

Find out more about Desert Center

If you're looking to discover somewhere new, look no further than Desert Center. Whether you're planning to stay for a night or for the week, the area around Desert Center has accommodations to fit every need. Search for hotels in Desert Center with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Desert Center hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Desert Center hotel deals are here with our lowest price guarantee.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com™ app users and Hotels.com™ Rewards members. Limited availability, blackout periods may apply.

Hotels.com Rewards members save more, as compared to non-members shopping on Hotels.com. Members 18+. Eligible properties only. Reward Night worth average daily rate of 10 stamps (excluding taxes/fees). Taxes/fees payable on reward night. Booking exclusions apply, see terms https://ca.hotels.com/lp/b/terms-of-service?pos=HCOM_CA&locale=en_CA.