Hotels in Southern Minnesota

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Where to stay in Southern Minnesota?

Holiday Inn Express Rochester South - Mayo Area by IHG
Exterior

Holiday Inn Express Rochester South - Mayo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (1002)
The price is CA $127
CA $147 total
includes taxes & fees
Feb 16 - Feb 17
Holiday Inn Express Rochester South - Mayo Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Southern Minnesota

Rochester showing a city and skyline

Downtown Rochester

Rochester's Downtown Rochester neighborhood has a host of places to visit such as Mayo Civic Center and Rochester Civic Theater.

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Downtown Rochester

Top landmarks in Southern Minnesota

Winona State University

Winona State University

Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.

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Winona State University

Learn more about Southern Minnesota

Southern Minnesota is applauded for its opera and entertainment with such cultural attractions as Mayo Clinic Health System Event Center and August Schell Museum of Brewing. This family-friendly city has something for everyone including its university life, restaurants, and sights like Mount Kato Ski Area and Blakeslee Stadium.

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Rochester showing a city and skyline
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Frequently asked questions

What accommodations do travelers like in Southern Minnesota?
Round Barn Farm B & B Event Center, Hilton Rochester Mayo Clinic Area and Alexander Mansion Bed and Breakfast are all properties that our guests really like.
Can I book refundable accommodations in Southern Minnesota?
If you’re looking for the flexibility to change your travel plans to Southern Minnesota, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Which Southern Minnesota hotels do our guests like for their terrific location?
Our guests rave about the location of these properties: Kahler Inn and Suites - Mayo Clinic Area, Kahler Grand Hotel and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S. For a quiet locale, travelers like Best Western Rochester Hotel Mayo Clinic Area/St. Mary’s.
Where should I consider staying in Southern Minnesota if I'm looking for a cheap accommodation?
Two inexpensive options worth considering are Hampton Inn Rochester-South and AmericInn by Wyndham Mankato Event Center. You can browse more choices on our site, including 32 motels.
Where can I stay in Southern Minnesota if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, review our selection of 417 vacation homes. In addition, there are 134 apartments and 47 condos.
Why should I book my Southern Minnesota accommodation with Hotels.com?
There are plenty of reasons to book your Southern Minnesota travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.