Hotels in Mesopotamia

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Where to stay in Mesopotamia?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesopotamia

Learn more about Mesopotamia

Notable for its natural beauty, Mesopotamia features attractions such as Termas de Chajarí and Termas Federacion Water Park. This romantic city has something for everyone including sights like Termas de Federacion and Concordia Speedway.

Mesopotamia showing a river or creek and forests

Frequently asked questions

What hotels do travelers like in Mesopotamia?
Casa Chic Carmelo, Club Valle Termal Resort and Costarenas Hotel & Spa are all accommodations that are popular with guests.
Can I book a refundable accommodation in Mesopotamia?
If you’re looking for the flexibility to change your plans to Mesopotamia, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where should I consider staying in Mesopotamia if I want a budget-friendly accommodation?
An inexpensive option worth considering is O2 Gualeguaychú.
Where can I stay in Mesopotamia if I want a vacation rental instead of a traditional hotel?
Browse 13 vacation homes on our site. You also might want to consider one of 18 apartments or 10 cabins.
Why should I book my Mesopotamia hotel through Hotels.com?
There are lots of reasons to book your Mesopotamia trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.