Hotels in Clayton Station

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Tonight
May 17 - May 18
Tomorrow
May 18 - May 19
Next weekend
May 23 - May 25
In two weeks
May 30 - Jun 1

Where to stay in Clayton Station?

Drury Inn & Suites St. Louis Brentwood
Lobby

Drury Inn & Suites St. Louis Brentwood

3.0 star property
9.6 out of 10, Exceptional, (1011)
The price is CA $190
CA $226 total
includes taxes & fees
May 22 - May 23
Drury Inn & Suites St. Louis Brentwood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Clayton Station, MO

Showing deals for:May 30 - Jun 1

Image gallery for The Royal Sonesta Chase Park Plaza St. Louis

Seasonal outdoor pool
VIP Access

The Royal Sonesta Chase Park Plaza St. Louis

4.5 star property
St. Louis
9.0/10Wonderful (1,008 reviews)
15% off
Price is CA $404
per night
CA $1,035 total
includes taxes & fees
The Royal Sonesta Chase Park Plaza St. Louis

Top landmarks in Clayton Station

St. Louis Art Museum

St. Louis Art Museum

You can spend time studying the exhibits at St. Louis Art Museum during your travels in St. Louis. Experience the area's fascinating museums or attend a sporting event.

See properties in St. Louis Art Museum
St. Louis Art Museum
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to get 25% or more off selected hotels, plus 1 reward night for every 10 nights you stay. Book by May 26 and travel by Sep 30, 2025. See terms*
Sign in or join for free

Find out more about Clayton Station

Find out more about Clayton Station

Where is Clayton Station?

Clayton Station is located in Clayton. If you want to find things to do in the area, you may want to check out Enterprise Center and St. Louis Zoo.

Where Can I Stay near Clayton Station?

We've got 14 hotels you can pick from within a mile of Clayton Station. You may want to consider one of these options that are popular with our guests:

Clayton Plaza Hotel & Extended Stay

  • hotel • Free breakfast • Free WiFi • Sauna • Central location

Le Méridien St. Louis Clayton

  • hotel • Free WiFi • Restaurant • Outdoor pool • Attentive staff

The Ritz-Carlton, St. Louis

  • hotel • Free WiFi • Restaurant • Fitness center • Attentive staff

Homewood Suites by Hilton St Louis - Galleria

  • hotel • Free breakfast • Free WiFi • 24-hour fitness center • Attentive staff

Things to See and Do near Clayton Station

What to See near Clayton Station

  • Enterprise Center
  • St. Louis Union Station
  • Busch Stadium
  • Gateway Arch
  • Washington University in St. Louis

Things to Do near Clayton Station

  • St. Louis Zoo
  • Saint Louis Galleria Mall
  • St. Louis Art Museum
  • Missouri History Museum
  • The Muny Theater

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com™ app users and Hotels.com™ Rewards members. Limited availability, blackout periods may apply.

Hotels.com Rewards members save more, as compared to non-members shopping on Hotels.com. Members 18+. Eligible properties only. Reward Night worth average daily rate of 10 stamps (excluding taxes/fees). Taxes/fees payable on reward night. Booking exclusions apply, see terms https://ca.hotels.com/lp/b/terms-of-service?pos=HCOM_CA&locale=en_CA.