MainStay Suites Rochester South Mayo Clinic
Hotel in Rochester





Experience the comfort of MainStay Suites Rochester South Mayo Clinic, where modern amenities meet thoughtful touches. Connect with in-room WiFi, unwind with a cup of coffee in the lobby, and take advantage of laundry facilities. The 24-hour front desk is always ready to help.
Good
Popular amenities
- Pet-friendly
- Non-smoking
- Laundry facilities
- 24/7 front desk
- Free parking
- Air conditioning
Main amenities (7)
- Housekeeping (on request)
- 24-hour front desk
- Coffee/tea in a common area
- Air conditioning
- Front-desk safe
- Vending machine
- Self-serve laundry
Feel at home (6)
- Kitchen
- Private bathroom
- Premium TV channels
- Laundry facilities
- Coffee/tea maker
- Elevator
CA $77
CA $88 total
includes taxes & fees
Dec 9 - Dec 10
Room options
Check availability for these dates
Showing 6 of 6 rooms

Standard Room, 1 Queen Bed, Non Smoking
Very good
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 2
- 1 Queen Bed

Standard Room, 2 Double Beds, Non Smoking
Good
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 4
- 2 Double Beds

Standard Room, 1 King Bed, Non Smoking (Pet Friendly)
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 2
- 1 King Bed

Standard Room, 1 King Bed, Non Smoking
Exceptional
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 2
- 1 King Bed

Room, 1 Queen Bed, Accessible, Non Smoking
Very good
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 2
- 1 Queen Bed

Room, 1 King Bed, Non Smoking
Highlights
Air conditioning
Kitchen
Refrigerator
Flat-screen TV
Shower/tub combination
Private bathroom
Microwave
Coffee/tea maker
- Sleeps 2
- 1 King Bed
Similar properties

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
- Pool
- Free breakfast
- Pet-friendly
- Free parking
Good
1,017 reviews
CA $95
CA $109 total
includes taxes & fees
Dec 6 - Dec 7

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
- Free breakfast
- Free parking
- Free WiFi
- Connecting rooms available
Good
1,002 reviews
CA $89
CA $102 total
includes taxes & fees
Dec 12 - Dec 13

Super 8 by Wyndham Rochester Mayo Clinic Area
- Free breakfast
- Free parking
- Free WiFi
- Connecting rooms available
Good
1,004 reviews
CA $71
CA $82 total
includes taxes & fees
Dec 14 - Dec 15

Extended Stay America Suites Rochester North
- Free breakfast
- Pet-friendly
- Free parking
- Free WiFi
Good
677 reviews
CA $88
CA $101 total
includes taxes & fees
Dec 18 - Dec 19

Spark by Hilton Rochester South
- Pool
- Free breakfast
- Pet-friendly
- Free parking
Exceptional
298 reviews
CA $96
CA $111 total
includes taxes & fees
Jan 4 - Jan 5, 2026

Quality Inn near Medical Center
- Pool
- Free breakfast
- Free parking
- Internet access
Good
804 reviews
CA $82
CA $94 total
includes taxes & fees
Dec 12 - Dec 13

AmericInn by Wyndham Rochester Near Mayo Clinic
- Pool
- Free breakfast
- Spa
- Pet-friendly
Very good
1,124 reviews
CA $102
CA $117 total
includes taxes & fees
Dec 12 - Dec 13

Baymont by Wyndham Rochester Mayo Clinic Area
- Pool
- Free breakfast
- Free parking
- Free WiFi
Good
716 reviews
CA $83
CA $96 total
includes taxes & fees
Dec 12 - Dec 13

Motel 6 Rochester, MN
- Pet-friendly
- Free parking
- Free WiFi
- Connecting rooms available
392 reviews
CA $69
CA $80 total
includes taxes & fees
Dec 18 - Dec 19

Med City Inn & Suites - Mayo Clinic Area
- Pool
- Free breakfast
- Pet-friendly
- Free parking
Good
1,003 reviews
CA $112
CA $129 total
includes taxes & fees
Dec 6 - Dec 7
Sign in to view eligible discounts and perks. More rewards for more adventures!
About the area

55 Woodlake Dr SE, Rochester, MN, 55904
About this property
MainStay Suites Rochester South Mayo Clinic
At MainStay Suites Rochester South Mayo Clinic, you'll be within a 10-minute drive of Mayo Clinic and Mayo Clinic Hospital - Saint Marys Campus. Free perks include WiFi and self parking.
At a glance
Property amenities
Room amenities
Frequently asked questions
Have a question?
Get instant answers with AI powered search of property information and reviews.
Most popular destinations
Hotels
Grand View LodgeHarrah’s Laughlin - A Caesars Rewards DestinationMystic Lake Casino HotelSea Mountain Inn Nude Resort and Spa - Adults OnlyHyatt Regency Mission Bay Spa and MarinaShooting Star Casino & HotelC'mon Inn Hotel & SuitesFairfield Inn & Suites East Grand Forks
Canad Inns Destination Center Grand ForksHyatt Vacation Club at Desert OasisSix Flags Great Escape Lodge & Indoor WaterparkAngel Of The Winds Casino ResortThe Westin Mission Hills Resort Villas, Palm SpringsGrand Casino HinckleyAkwesasne Mohawk Casino Resort and Players InnCountry Inn & Suites by Radisson Albertville near Outlet Mall