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1 room, 2 adults

Twentyone Hotel, Rome

4-star4 stars
Via Cola di Rienzo 23, Rome, RM, 192, Italy

4-star hotel with restaurant, near Piazza del Popolo
  • Free WiFi
  • Collect stampsYou can collect™ Rewards stamps here

Restrictions related to your trip

COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.  Check restrictions for your trip.

  • Very clean, nice location, cool decoration, friendly staff!Jul. 24, 2019
  • Property itself excellent. Clean, well maintained, A/C worked well (a must for the 35…Jul. 12, 2019

Twentyone Hotel, Rome

from $154 CAD
  • Double Room Single Use
  • Standard Double Room
  • Deluxe Double or Twin Room
  • Standard Triple Room
  • Standard Twin Room, 2 Single Beds
  • Junior Suite

What’s around Twentyone Hotel, Rome


  • In Vatican
  • Piazza del Popolo - 7 min walk
  • Via del Corso - 8 min walk
  • Villa Borghese - 11 min walk
  • Castel Sant'Angelo - 12 min walk
  • Piazza di Spagna - 15 min walk
  • Piazza Navona - 15 min walk
  • Spanish Steps - 18 min walk

Getting around

  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 37 min drive
  • Ciampino Airport (CIA) - 41 min drive
  • Rome Piazzale Flaminio Station - 11 min walk
  • Rome San Pietro Station - 29 min walk
  • Rome Euclide Station - 4 min drive
  • Lepanto Station - 8 min walk
  • Flaminio - Piazza del Popolo Station - 8 min walk
  • Ottaviano - San Pietro - Musei Vaticani Station - 14 min walk
  • Airport shuttle (surcharge)

At a glance

Key facts

Hotel size

  • This hotel has 86 rooms
  • This hotel is arranged over 8 floors


  • Check-in time 2 PM-midnight
  • Check-out time is 11 AM
  • Express check-in

Restrictions related to your trip

  • COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.
Front desk staff will greet guests on arrival.

Required at check-in

  • Credit card, debit card, or cash deposit required for incidental charges

  • Government-issued photo ID may be required

Travelling with others


  • One child stays free when occupying the parent or guardian's room, using existing bedding


  • Pets not allowed (service animals welcome)


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Airport shuttle (available 24 hours)*


  • Covered onsite self parking (EUR 25 per day; includes in/out privileges)

  • Wheelchair-accessible parking on site

Payment types at the property

Other information

  • Smoke-free property
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Buffet breakfast daily (surcharge)
  • Restaurant
  • Bar/lounge
  • Snack bar/deli
  • Room service (during limited hours)
Things to do
  • Scooter/moped rentals nearby
Working away
  • Conference space
  • 24-hour front desk
  • Concierge services
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Laundry facilities
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Year Built - 2009
  • Elevator
  • Garden
  • Television in common areas
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower
  • Wheelchair-accessible parking
  • Wheelchair-accessible public restroom
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible on-site restaurant
  • Grab bar - near toilet
  • Bathroom emergency pull cord
Languages Spoken
  • English
  • French
  • German
  • Italian
  • Moldovan
  • Russian
  • Spanish

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Minibar
  • Iron/ironing board (on request)
Sleep well
  • Soundproofed rooms
  • Premium bedding
Things to enjoy
  • Individually decorated
Freshen up
  • Private bathroom
  • Shower only
  • Bidet
  • Free toiletries
  • Hair dryer
Be entertained
  • Flat-screen TV
  • Pay movies
  • Premium TV channels
Stay connected
  • Desk
  • Free WiFi
  • Phone
  • Daily housekeeping
  • In-room safe

Twentyone Hotel, Rome’s small print

Also known as

  • Hotel Twentyone
  • Twentyone Hotel Hotel Rome
  • Twentyone Hotel
  • Twentyone Hotel Rome
  • Twentyone Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Hotel


All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.

Cash transactions at this property cannot exceed EUR 1999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.

Guests can rest easy knowing there's a fire extinguisher, a smoke detector, and a first aid kit on site.

This property advises that enhanced cleaning and guest safety measures are currently in place.

Disinfectant is used to clean the property; commonly-touched surfaces are cleaned with disinfectant between stays; bed sheets and towels are laundered at a temperature of at least 60°C/140°F.

Social distancing measures are in place; staff at the property wear personal protective equipment; a shield is in place between staff and guests in main contact areas; periodic temperature checks are conducted on staff; temperature checks are available to guests; guests are provided with hand sanitizer.

Contactless check-in is available.

Individually-wrapped food options are available for breakfast, lunch, and dinner, and also through room service.

For transfers, guests must contact the property before arrival at the number on the booking confirmation.

This property accepts credit cards. Cash is not accepted.

Mandatory fees

You’ll be asked to pay the following charges at check-in or check-out:

  • A tax is imposed by the city: EUR 6 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

Optional extras

Covered self parking costs EUR 25 per day with in/out privileges

Buffet breakfast is offered for an extra charge of EUR 8 per person (approximately)

Airport shuttle service is offered for an extra charge of EUR 65 per vehicle (one-way)

We have included all charges provided to us by this property. However, charges can vary, for example, based on length of stay or the unit you book.

FAQs for Twentyone Hotel, Rome

  • Does Twentyone Hotel offer free cancellation for a full refund?
    Yes, Twentyone Hotel does have fully refundable rooms available to book on our site, which can be cancelled up to a few days before check-in. Just make sure to check this property's cancellation policy for the exact terms and conditions.
  • What are the cleanliness and hygiene measures currently in place at Twentyone Hotel?
    This property confirms that disinfectant is used to clean the property. Furthermore, guests are provided with hand sanitizer, social distancing measures are in place, and gives staff personal protective equipment. Please note that this information has been provided by our partners.
  • Is parking offered on site at Twentyone Hotel?
    Yes. Self parking costs EUR 25 per day.
  • Are pets allowed at Twentyone Hotel?
    Sorry, pets aren't allowed, but service animals are welcome.
  • What are the check-in and check-out times at Twentyone Hotel?
    You can check in from 2 PM - midnight. Check-out time is 11 AM. Express check-in and contactless check-in are available.
  • Are there restaurants at or near Twentyone Hotel?
    Yes, there's an onsite restaurant. Nearby restaurants include Ai Villini (3-min walk), Brown & Co. (3-min walk), and Il Belli (4-min walk).
  • Is airport shuttle service offered by Twentyone Hotel?
    Yes, an airport shuttle is available. The charge is EUR 65 per vehicle one-way.
  • What is there to do at Twentyone Hotel and nearby?
    Twentyone Hotel has a garden.

Recent reviews

Very Good 8.0 From 304 reviews

Very Good 8.0
Nice hotel close to all attractions.
Nice hotel, well located within walking distance to all sights. Hotel staff largely helpful, although afternoon shift check in person indifferent. Poor wifi, hotel has to deal with this asap. Breakfasts are good, make sure you include this at time of booking.
David, ca4 night romance trip
Good 6.0
Good location
Wendy, ca12 night trip
Exceptional 10.0
Highly recommended!
SERVICE: The front staff are friendly, helpful and speak perfect English. They recommended some very good restaurants and places to visit. CLEANLINESS: The room was kept impeccable all week. The hotel shared areas and restaurant are top notch clean. COMFORT: The room was modern and just spacious enough. It has a minibar and safe. The bathroom has top quality equipment with a great glass shower. One small improvement would be a shelf to put toiletries. The only disappointment for this hotel was the bed. It was way too stiff … and I have visited hundreds of hotels worldwide. CONDITION: The hotel looks brand new. It is modern and trendy. LOCAL AREA: Amazing location in the Prati area. It is walking distance (~15 min) from the Vatican, Castel Sant Angelo, Piazza del Popolo and Piazza Navona. If you can walk longer distances, you can visit all of Rome from this location. OVERALL: I highly recommend this hotel. Thank you Hotel21 for a great Roman Holiday!
Charles, ca7 night romance trip
Exceptional 10.0
Very nice hotel and ideal, helpful staff. The restaurant is great too!
Valerie, ca1 night trip
Very Good 8.0
Location is great close to all attractions. Hotel staff are friendly and explain where to go etc
ca4 night trip
Very Good 8.0
Small boutique hotel. Close to shopping an amenities. It is within walking distance to the Vatican. We ate every meal in the hotel restaurant during our 2 day stay. The food we chose was delicious. The service we received was great. We would definitely return and recommend this hotel.
Lencha, ca2 night trip
Very Good 8.0
The hotel is in a fantastic location close to the
The hotel is in a fantastic location close to the Vatican. It was very clean and monitor inside. A bit warm although the air conditioning was working. However the beds were very uncomfortable and going to need to be changed along with the pillows as well. Other than that it was very good
DARRELL, ca2 night trip with friends
Exceptional 10.0
My stay here was exceptional coinsidering before this i was stayin in a 5 star which did not compare to this hotel. The staff were very accomadating and arranged a car service for me for an early morning flight.
Kevin, ca3 night trip
Exceptional 10.0
i have stayed here before. great staff, rooms clean and roomy, great location, few blocks from subway and price is good for what you receive
jay, ie1 night trip
Poor 2.0
The hotel was closed but they refused to refund us. They offered only a voucher to use within 12 months which is not suitable. Terrible service to hold back amount paid and not deliver the service. No comment from management other than “we are closed, here is your voucher” and haven’t heard from them again. Expedia customer service said I am entitled to a refund as the property is closed but no further communication from Twentyone Hotel.
gb2 night romance trip

Twentyone Hotel, Rome