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All properties in Rome, Lazio, Italy
1 room, 2 adults

Twentyone Hotel, Rome

4-star4 stars
Via Cola di Rienzo 23, Rome, RM, 00192, Italy

4-star hotel with restaurant, near Piazza del Popolo
  • Free WiFi
  • Collect stampsYou can collect™ Rewards stamps here
  • Very clean, nice location, cool decoration, friendly staff!Jul. 31, 2019
  • Property itself excellent. Clean, well maintained, A/C worked well (a must for the 35…Jul. 22, 2019

Twentyone Hotel, Rome

from $93 CAD
  • Double Room Single Use
  • Standard Double Room
  • Deluxe Double or Twin Room
  • Standard Triple Room
  • Standard Twin Room, 2 Single Beds
  • Junior Suite

What’s around Twentyone Hotel, Rome


  • In Vatican
  • Piazza del Popolo - 7 min walk
  • Via del Corso - 8 min walk
  • Villa Borghese - 11 min walk
  • Castel Sant'Angelo - 12 min walk
  • Piazza di Spagna - 15 min walk
  • Piazza Navona - 15 min walk
  • Spanish Steps - 18 min walk

Getting around

  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 39 min drive
  • Ciampino Airport (CIA) - 40 min drive
  • Rome Piazzale Flaminio Station - 11 min walk
  • Rome San Pietro Station - 29 min walk
  • Rome Euclide Station - 4 min drive
  • Lepanto Station - 8 min walk
  • Flaminio - Piazza del Popolo Station - 8 min walk
  • Ottaviano - San Pietro - Musei Vaticani Station - 14 min walk
  • Airport shuttle (surcharge)

At a glance

Key facts

Hotel size

  • This hotel has 86 rooms
  • This hotel is arranged over 8 floors


  • Check-in time 2 PM-midnight
  • Check-out time is 11 AM
  • Express check-in
Front desk staff will greet guests on arrival.
24-hour airport shuttle service is available on request. Fees may apply. Contact the property in advance to make arrangements.

Required at check-in

  • Credit card, debit card, or cash deposit required for incidental charges

  • Government-issued photo ID may be required

Travelling with others


  • One child stays free when occupying the parent or guardian's room, using existing bedding


  • Pets not allowed


  • Free WiFi and wired Internet access in public areas

  • Free WiFi and wired Internet access in rooms



  • Airport shuttle (available 24 hours) *


  • Self parking *

Payment types at the property

Other information

  • Smoke-free property
* See small print for additional details or extra charges

In the hotel

Food and drink
  • Buffet breakfast daily (surcharge)
  • Restaurant
  • Bar/lounge
  • Room service (during limited hours)
Things to do
  • Scooter/moped rentals nearby
Working away
  • Conference space
  • 24-hour front desk
  • Concierge services
  • Tours/ticket assistance
  • Limo or Town Car service available
  • Dry cleaning/laundry service
  • Laundry facilities
  • Luggage storage
  • Multilingual staff
  • Porter/bellhop
  • Year Built - 2009
  • Elevator
  • Garden
  • Television in common areas
  • Accessible bathroom
  • In-room accessibility
  • Roll-in shower
  • Wheelchair accessible
  • Wheelchair-accessible path of travel
  • Grab bar - near toilet
  • Bathroom emergency pull cord
Languages Spoken
  • English
  • French
  • German
  • Italian
  • Moldovan
  • Russian
  • Spanish

In the room

Home comforts
  • In-room climate control (air conditioning)
  • Minibar
  • Iron/ironing board (on request)
Sleep well
  • Premium bedding
Things to enjoy
  • Individually decorated
Freshen up
  • Private bathroom
  • Shower only
  • Bidet
  • Free toiletries
  • Hair dryer
Be entertained
  • Flat-screen TV
  • Pay movies
  • Premium TV channels
Stay connected
  • Desk
  • Free WiFi
  • Phone
  • Daily housekeeping
  • In-room safe

Twentyone Hotel, Rome’s small print

Also known as

  • Hotel Twentyone
  • Twentyone Hotel Hotel Rome
  • Twentyone Hotel
  • Twentyone Hotel Rome
  • Twentyone Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Rome
  • Twentyone Hotel Hotel


All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.

Cash transactions at this property cannot exceed EUR 1999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.

Guests can rest easy knowing there's a fire extinguisher, a smoke detector, and a first aid kit on site.

This property advises that enhanced cleaning and guest safety measures are currently in place.

Disinfectant is used to clean the property; commonly-touched surfaces are cleaned with disinfectant between stays; bed sheets and towels are laundered at a temperature of at least 60°C/140°F.

Social distancing measures are in place; staff at the property wear personal protective equipment; a shield is in place between staff and guests in main contact areas; periodic temperature checks are conducted on staff; temperature checks are available to guests.

Contactless check-in is available.

Individually-wrapped food options are available for breakfast, lunch, and dinner, and also through room service.

For transfers, guests must contact the property before arrival at the number on the booking confirmation.

Mandatory fees

You’ll be asked to pay the following charges at check-in or check-out:

  • A tax is imposed by the city: EUR 6 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

Optional extras

Self parking costs EUR 20 per day

Buffet breakfast is offered for an extra charge of EUR 8 per person (approximately)

Airport shuttle service is offered for an extra charge of EUR 65 per vehicle (one-way)

We have included all charges provided to us by this property. However, charges can vary, for example, based on length of stay or the unit you book.

FAQs for Twentyone Hotel, Rome

  • Does Twentyone Hotel offer free cancellation for a full refund?
    Yes, Twentyone Hotel does have fully refundable rooms available to book on our site, which can be cancelled up to a few days before check-in. Just make sure to check this property's cancellation policy for the exact terms and conditions.
  • Is parking offered at Twentyone Hotel?
    Yes. Self parking costs EUR 20 per day.
  • Are pets allowed at Twentyone Hotel?
    Sorry, pets aren't allowed.
  • What are the check-in and check-out times at Twentyone Hotel?
    You can check in from 2 PM to midnight. Check-out time is 11 AM.
  • Are there restaurants at or near Twentyone Hotel?
    Yes, there's an onsite restaurant. Nearby restaurants include Portofino (3-min walk), L'Arancina (3-min walk), and Brown & Co. (3-min walk).
  • Is airport shuttle service offered by Twentyone Hotel?
    Yes, an airport shuttle is available. The charge is EUR 65 per vehicle one-way.

Recent reviews

Very Good 8.2 From 389 reviews

Very Good 8.0
Nice hotel close to all attractions.
Nice hotel, well located within walking distance to all sights. Hotel staff largely helpful, although afternoon shift check in person indifferent. Poor wifi, hotel has to deal with this asap. Breakfasts are good, make sure you include this at time of booking.
David, ca4 night romance trip
Good 6.0
Good location
Wendy, ca12 night trip
Exceptional 10.0
Highly recommended!
SERVICE: The front staff are friendly, helpful and speak perfect English. They recommended some very good restaurants and places to visit. CLEANLINESS: The room was kept impeccable all week. The hotel shared areas and restaurant are top notch clean. COMFORT: The room was modern and just spacious enough. It has a minibar and safe. The bathroom has top quality equipment with a great glass shower. One small improvement would be a shelf to put toiletries. The only disappointment for this hotel was the bed. It was way too stiff … and I have visited hundreds of hotels worldwide. CONDITION: The hotel looks brand new. It is modern and trendy. LOCAL AREA: Amazing location in the Prati area. It is walking distance (~15 min) from the Vatican, Castel Sant Angelo, Piazza del Popolo and Piazza Navona. If you can walk longer distances, you can visit all of Rome from this location. OVERALL: I highly recommend this hotel. Thank you Hotel21 for a great Roman Holiday!
Charles, ca7 night romance trip
Very Good 8.0
The hotel is in a fantastic location close to the
The hotel is in a fantastic location close to the Vatican. It was very clean and monitor inside. A bit warm although the air conditioning was working. However the beds were very uncomfortable and going to need to be changed along with the pillows as well. Other than that it was very good
DARRELL, ca2 night trip with friends
Exceptional 10.0
i have stayed here before. great staff, rooms clean and roomy, great location, few blocks from subway and price is good for what you receive
jay, ie1 night trip
Good 6.0
Great location, but lacking in services.
We have stayed at this hotel before and the location is great, but it is starting to look a little tired. For a 4 Star hotel I was also a bit disappointed with the facilities or lack of. There was no tea / coffee facilities within the room. The Hotel Bar shut at midnight, and bar staff were reluctant to give us glasses for drinks in our room. The Hotel is fine if your just looking for somewhere to crash after a day out exploring, but its not somewhere to spend any length of time at.
Thomas, gb5 night family trip
Fair 4.0
Amazing location, parking available but bad smell
Location is excellent, in a good neighborhood, walking distance to the historical center and to Vaticano. There is parking available per 25 euros a night. Unfortunately, there are some bad aspects related to this hotel: - the walls and windows are not soundproof, so it is possible to hear everything across the walls and from the street; - the bed is too hard, not comfort at all, and; - there is a strong smoking smell that comes from the bathroom.
Cristiane, us2 night family trip
Fair 4.0
Bad attitude and un friendly front desk staff
The front desk staff are not very friendly and warm. Very cold and unhelpful. Will not stay here again.
Amish, za3 night family trip
Exceptional 10.0
Lovely hotel
Really good location and price, lovely hotel and staff were very helpful! Would recommend highly
Lucy, gb3 night trip
Very Good 8.0
Close to Vatican city and city center. The breakfast was good and the room and decoration is quite elegant .
Lasse, us1 night romance trip

Twentyone Hotel, Rome

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