Hotels in Otay Mesa

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Otay Mesa?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
trending_down

Our prices for hotels in Otay Mesa are cheapest in March

See average prices and weather for all months

Price trends for hotels in Otay Mesa

Pricing is based on two traveller single night rates
Apr
CA $216
Average price during April is CA $216
May
CA $197
Average price during May is CA $197
Jun
CA $205
Average price during June is CA $205
Jul
CA $245
Average price during July is CA $245
Aug
CA $220
Average price during August is CA $220
Sep
CA $186
Average price during September is CA $186
Oct
CA $187
Average price during October is CA $187
Nov
CA $191
Average price during November is CA $191
Dec
CA $196
Average price during December is CA $196
Jan
CA $197
Average price during January is CA $197
Feb
CA $195
Average price during February is CA $195
Mar
CA $182
Average price during March is CA $182
Currently viewing crowd sizes and weather for April.

April

trending_flatModerate crowds
High 20°C / low 13°C. Sunny most days.
20°
weather_sun
April, Moderate crowds, average high temperature 20 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
20°
weather_sun
May, High crowds, average high temperature 20 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
23°
weather_sun
June, High crowds, average high temperature 23 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
25°
weather_sun
July, High crowds, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
26°
weather_sun
August, High crowds, average high temperature 26 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
26°
weather_sun
September, Moderate crowds, average high temperature 26 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
24°
weather_sun
October, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
21°
weather_sun
November, Low crowds, average high temperature 21 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
18°
weather_sun
December, Low crowds, average high temperature 18 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
18°
weather_sun
January, Low crowds, average high temperature 18 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
18°
weather_sun
February, Low crowds, average high temperature 18 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
18°
weather_sun
March, Moderate crowds, average high temperature 18 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
Monthly weather averages (˚C)

Top landmarks in San Diego

A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to get 25% or more off selected hotels, plus 1 reward night for every 10 nights you stay. Book by May 26 and travel by Sep 30, 2025. See terms*

Find out more about Otay Mesa

Find out more about Otay Mesa

Discover the Hidden Shores: Otay Mesa's Coastal Wonderland

Discover Otay Mesa, a hidden gem in San Diego, California, where the allure of border culture meets vibrant local charm. This unique destination boasts a fascinating blend of urban and natural attractions, including the stunning Otay Valley Regional Park, perfect for hiking and birdwatching. Just a short drive away, indulge in the sun-soaked shores of Pacific Beach. With its eclectic dining scene and proximity to downtown San Diego, Otay Mesa is ideal for adventurous travellers seeking a taste of local life and scenic landscapes. Experience the warmth of California’s southernmost border and make unforgettable memories in this captivating locale. For great hotel rates in Otay Mesa, be sure to check out Hotels.com's Last-Minute DealsOpens in a new window on travel.

Top locations to stay in Otay Mesa

Otay Mesa, San Diego, is a vibrant area for travellers. The San Ysidro Border Crossing offers easy access to Mexico, making it ideal for adventurous first-time visitors. Seaport Village, with its picturesque waterfront and shopping options, provides a relaxing experience. Accommodations around Otay Mesa range from budget motels to comfortable hotels, ensuring options for every traveller’s needs. For a memorable stay, consider hotels near the border or in Seaport Village for a mix of convenience and leisure. These are some of the hotels preferred by our travelers in Otay Mesa:

  1. Near Seaport VillageOpens in a new window: This vibrant area is perfect for adventure seekers and families, offering a mix of outdoor activities and a lively atmosphere. With its proximity to the water, visitors can enjoy a variety of water sports and recreational activities. It’s also well-suited for business travellers, featuring hotels equipped with essential amenities for meetings and work-related needs. For comfortable accommodations, consider Embassy Suites by Hilton San Diego Bay DowntownOpens in a new window, a 4-star hotel ideal for adventure, business, and family vacations. It provides services such as business amenities, adventure sports options, and child-friendly facilities. Another option is Manchester Grand Hyatt San DiegoOpens in a new window, also a 4-star hotel, which offers similar amenities and adventure activities like surfing and kayaking. Lastly, The Guild HotelOpens in a new window, a 4-star hotel, excels in providing services for business travellers and families, featuring amenities like a coworking space and various water sports options nearby, ensuring a pleasant stay for all guests.

Things to do in Otay Mesa for first times

Otay Mesa offers a captivating blend of coastal beauty and vibrant culture, making it an ideal three-day getaway. Visitors can enjoy sun-soaked beaches, scenic parks, and opportunities for hiking, while indulging in diverse shopping, lively dancing, and engaging theatre performances. The area's dynamic atmosphere promises an unforgettable experience. Here's a quick itinerary to make the most of your trip to Otay Mesa:

  • Day 1: Begin your San Diego adventure at Coronado Beach, where golden sands and stunning views of the Pacific Ocean await. Take a leisurely stroll along the shoreline, soaking up the sun. Next, head over to Centennial Park, which offers beautiful vistas of the San Diego skyline—perfect for some memorable photos. Finally, make your way to Seaport Village, a charming waterfront shopping and dining area. Explore the unique shops, enjoy delicious local cuisine, and relax by the water as you watch the boats go by.
  • Day 2: Start your day at San Diego Bay, where you can take in the scenic views and perhaps even catch a ferry ride. After that, head to the Living Coast Discovery Center, an exciting place to learn about local wildlife and conservation efforts. Enjoy interactive exhibits and get close to native animals. You can visit the Living Coast Discovery Center again to explore more attractions or join a guided tour to enhance your experience.
  • Day 3: Your day begins at Imperial Beach, perfect for a stroll along the pier or beachcombing. Next, take a scenic drive across the San Diego-Coronado Bridge, which provides breathtaking views of the bay and city. Conclude your day at Silver Strand State Beach, a serene spot ideal for unwinding. Enjoy a picnic or simply relax by the beach, embracing the tranquil atmosphere as the sun sets over the horizon.

4 tips to find a great Otay Mesa hotel deal

  1. Book for the cheapest times: The most affordable time to visit Otay Mesa is during January, November, and December, when hotel prices are at their lowest. Domestic travellers should aim to book their flights at least 2 months in advance to secure better deals, while international travellers are advised to book at least 3 months ahead for greater savings. To fully experience the main attractions, including the beach, a stay of at least 2 to 3 days is recommended. This way, you can enjoy Otay Mesa on a budget while taking advantage of its great value for money.
  2. Look for last-minute deals on Hotels.com: If you're searching for last-minute deals in Otay Mesa, consider exploring the DealsOpens in a new window or Last-Minute DealsOpens in a new window sections on Hotels.com. Here, you could find competitive rates on hotels as your travel date approaches. To enhance your chances of scoring discounts, enable email alerts or push notifications from Hotels.com. This way, you’re more likely to stay informed about flash sales and exclusive promotions, allowing you to snag affordable accommodations in Otay Mesa.
  3. Be flexible with dates: Prices may fluctuate due to factors like the hotel's location, star rating, and the time of year. As a result, being flexible with your travel dates could mean you may save on hotel expenses in Otay Mesa.
  4. Consider your location: When making a reservation on Hotels.com for your holiday, take your location into account. Staying closer to major attractions or city centres may offer convenience, but it usually tends to come at a higher price. For more affordable rates, consider hotels in less central areas or neighbourhoods, striking a balance between cost and the ease of reaching the sites you want to explore.

Best time to go to Otay Mesa

Otay Mesa experiences its lowest average temperature in February, at 56.8°F (13.8°C), while August is the hottest month, with an average temperature of 72.3°F (22.4°C). December tends to be the wettest month. The peak travel months to visit Otay Mesa are June, July, and September, which see a higher number of tourists. During this peak period, the weather is sunny, accompanied by no rainfall. In contrast, January, October, and December are ideal if you're looking for a calmer vacation, marked by no to light rainfall and mostly sunny conditions.

What's Otay Mesa Like?

In Otay Mesa, you can spend time visiting the shops or simply enjoy the restaurants. Enjoy this a family-friendly neighborhood's beach views. In the larger area, you'll find top places to visit like San Ysidro Border Crossing. High Performance Center in Tijuana and Alameda Otay are a couple of more places to see nearby.

Where are the Best Places to Stay in Otay Mesa?

Here are our customers' favorite places to stay in Otay Mesa:

Quality Suites San Diego Otay Mesa

City-center hotel with outdoor pool
  • Free breakfast • Free parking • Free WiFi • Spa tub • Fitness center

Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel

Hotel with outdoor pool
  • Free breakfast • Free parking • Free WiFi • Fitness center • Attentive staff

How to Get to Otay Mesa

Flying to:

  • Tijuana Intl. Airport (TIJ), 0.9 mi (1.5 km) from Otay Mesa
  • San Diego Intl. Airport (SAN), 17.7 mi (28.4 km) from Otay Mesa
  • San Diego, CA (SEE-Gillespie Field), 18.4 mi (29.6 km) from Otay Mesa

Things to See and Do in and around Otay Mesa

Things to See near Otay Mesa:

  • San Ysidro Border Crossing (3.4 mi/5.5 km away)
  • High Performance Center in Tijuana (1.7 mi/2.7 km away)
  • Autonomous University of Baja California (1.9 mi/3.1 km away)
  • CAS Visa USA (3.8 mi/6 km away)
  • Tijuana Customs - Garita El Chaparral (3.8 mi/6.1 km away)

Things to Do near Otay Mesa:

  • Alameda Otay (2.4 mi/3.8 km away)
  • North Island Credit Union Amphitheatre (2.7 mi/4.4 km away)
  • Sesame Place San Diego (3 mi/4.8 km away)
  • Plaza Península Shopping Center (3.2 mi/5.2 km away)
  • Centro Cultural Tijuana (3.5 mi/5.7 km away)

When Is the Best Time to Visit San Diego?

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com™ app users and Hotels.com™ Rewards members. Limited availability, blackout periods may apply.

Hotels.com Rewards members save more, as compared to non-members shopping on Hotels.com. Members 18+. Eligible properties only. Reward Night worth average daily rate of 10 stamps (excluding taxes/fees). Taxes/fees payable on reward night. Booking exclusions apply, see terms https://ca.hotels.com/lp/b/terms-of-service?pos=HCOM_CA&locale=en_CA.