Hotels in Santa María

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Free cancellation options if plans change

Where to stay in Santa María?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa María

The region around Santa María is home to attractions such as Chivor Reservoir and Macanal Main Park.

Frequently asked questions

Can I book refundable accommodations in Santa María?
If you’re looking for the flexibility to change your plans to Santa María, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa María be like during my visit?
February and January are typically the warmest months in Santa María when the average temp is 54°F. August and September are the coldest months when the average temperature is 54°F. April and November are the months with the most rain.
Why should I book my Santa María hotel through Hotels.com?
There are lots of reasons to book your Santa María trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.