Hotels in Southwest Houston

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Tonight
Feb 24 - Feb 25
Tomorrow
Feb 25 - Feb 26
This weekend
Feb 28 - Mar 2
Next weekend
Mar 7 - Mar 9

Where to stay in Southwest Houston?

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (782)
The price is CA $138
CA $162 total
includes taxes & fees
Mar 24 - Mar 25
Comfort Suites near Texas Medical Center - NRG Stadium
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Southwest Houston

Default Image

The Galleria

Houston's lively The Galleria neighborhood offers lots of great attractions such as The Galleria and Williams Tower.

See properties in The Galleria
The Galleria

Top landmarks in Southwest Houston

Houston Zoo

Houston Zoo

It's feeding time at the zoo! If you can't resist those cuddly critters you might want to pay a trip to Houston Zoo, located 3.5 mi (5.6 km) from central Houston. Our travelers also like the museums and art galleries in the area. If you have fun at Houston Zoo, you'll love Houston Natural Science Museum and Children's Museum of Houston, both located nearby.

See properties in Houston Zoo
Houston Zoo

Learn more about Southwest Houston

Southwest Houston is admired for its sports and festivals while top attractions include NRG Stadium and Houston Zoo. The city has something for everyone including its live music, restaurants, and sights like Meyerland Plaza Shopping Center and Arena Theater.

See all hotels in Southwest Houston
Hermann Park featuring a garden and landscape views

Frequently asked questions

What accommodations do travelers recommend in Southwest Houston?
Hilton Garden Inn Houston Medical Center, TX, Blossom Hotel Houston and Palace Inn Blue US 59 & Gessner are all accommodations that are popular with guests.
Can I book refundable accommodations in Southwest Houston?
If you need the flexibility to change your travel plans to Southwest Houston, most hotels provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Which Southwest Houston hotels do guests like for their great location?
Travelers like these properties for their convenient location: The Royal Sonesta Houston Galleria, Sonesta ES Suites Houston Galleria and The Westin Galleria Houston. For quiet surroundings, guests like Sonesta Simply Suites Houston Galleria Medical Center.
Where can I stay in Southwest Houston if I want a budget-friendly accommodation?
Holiday Inn Express Houston - Galleria Area, an IHG Hotel and SureStay Plus Hotel by Best Western Houston Medical Center are two accommodations you might want to consider that’ll save you money. You may want to browse more choices on our site, including 14 motels.
Where can I stay in Southwest Houston if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 485 vacation homes. In addition, there are 829 apartments and 134 condos.
Why should I book my Southwest Houston hotel with Hotels.com?
There are lots of reasons to book your Southwest Houston trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.