Photo by Michael Schuier

Hotels in Ladys Island

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Check prices for these dates

Tonight
May 22 - May 23
Tomorrow
May 23 - May 24
This weekend
May 23 - May 25
Next weekend
May 30 - Jun 1

Where to stay in Ladys Island?

Circa 1785
Porch

Circa 1785

4.0 star property
9.6 out of 10, Exceptional, (92)
The price is CA $278
CA $306 total
includes taxes & fees
Jun 1 - Jun 2
Circa 1785
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Ladys Island

Bay Street

Bay Street

During your trip to Beaufort, you can enjoy retail therapy at Bay Street. While in this family-friendly area, you can enjoy the restaurants.

See properties in Bay Street
Bay Street

Learn more about Ladys Island

Ladys Island is well-known for its attractions such as Sanctuary Golf Club and Coosaw Island.

See all hotels in Ladys Island
Photo by Michael Schuier
Open Photo by Michael Schuier
A tranquil hotel pool encircled by beautiful arches

Summer Getaway Sale

Sign in to get 25% or more off selected hotels, plus 1 reward night for every 10 nights you stay. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What hotels do travelers recommend in Ladys Island?
Guests like Quality Inn At Town Center, SpringHill Suites by Marriott Beaufort and Tru by Hilton Beaufort, SC.
Can I book refundable accommodations in Ladys Island?
If you need the flexibility to change your plans to Ladys Island, most accommodations provide refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Ladys Island if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 31 vacation homes. In addition, you can choose from 7 apartments.
Why should I book my Ladys Island hotel with Hotels.com?
There are plenty of reasons to book your Ladys Island travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com™ app users and Hotels.com™ Rewards members. Limited availability, blackout periods may apply.

Hotels.com Rewards members save more, as compared to non-members shopping on Hotels.com. Members 18+. Eligible properties only. Reward Night worth average daily rate of 10 stamps (excluding taxes/fees). Taxes/fees payable on reward night. Booking exclusions apply, see terms https://ca.hotels.com/lp/b/terms-of-service?pos=HCOM_CA&locale=en_CA.